Mesothelioma Affects the tissue that surrounds the lungs (pleura)

Mayo Clinic
Mesothelioma
General view
Malignant mesothelioma is a type of cancer that occurs in the thin layer of tissue that lines most internal organs (mesothelium).

Mesothelioma is an aggressive and deadly form of cancer. There are treatments available for mesothelioma, but for many people who suffer from this disease, the cure is not possible.

Doctors divide mesothelioma into various types according to what part of the mesothelium is affected. In general, mesothelioma affects the tissue that surrounds the lungs (pleura). This type is called "pleural mesothelioma." Other less common types of mesothelioma affect the tissue of the abdomen (peritoneal mesothelioma), the tissue that surrounds the heart, and the tissue that lines the testicles.

Mesothelioma does not include a non-cancerous (benign) form of tumor that occurs in the chest and is sometimes called "benign mesothelioma" or "solitary fibrous tumor." symptom

The signs and symptoms of mesothelioma vary depending on where the cancer appears.
Pleural mesothelioma, which affects the tissue surrounding the lungs, causes signs and symptoms that may include the following:
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Chest pain below the rib cage Painful cough Shortness of breath Unusual bundles of tissue under the skin of the chest Thinning without apparent cause

Peritoneal mesothelioma, which occurs in the tissue of the abdomen, causes signs and symptoms that may consist of the following:

Abdominal pain Abdominal swelling Lumps of tissue in the abdomen Thinning without apparent cause

Other forms of mesothelioma

The signs and symptoms of other types of mesothelioma are not clear, since these forms of the disease are very rare.

Pericardial mesothelioma, which affects the tissue around the heart, causes signs and symptoms, such as difficulty breathing and chest pains.

Tissue mesothelioma, which affects the tissue around the testicles, can first be detected as swelling or as a mass in a testicle. When to see the doctor

If you have signs and symptoms that may indicate mesothelioma, see your doctor. The signs and symptoms of mesothelioma are not specific to this disease and, due to the rarity of mesothelioma, are more likely to be related to other diseases. If some of the signs and symptoms seem unusual or bothersome, ask your doctor to evaluate them. Tell the doctor if you have been exposed to asbestos. Causes

In general, cancer begins when there is a series of genetic mutations within a cell, which causes the cell to grow and multiply without control. It is not clear what causes the initial genetic mutations that cause mesothelioma, although researchers have identified factors that may increase the risk. It is likely that cancer cases are formed due to an interaction between many factors, such as hereditary disorders, the environment, health status and lifestyle choices.

Risk factor's Exposure to asbestos: the main risk factor for mesothelioma Asbestos is a mineral found naturally in the environment. Asbestos fibers are strong and resistant to heat, which makes them useful for a wide range of applications, such as insulation, brakes, tiles, flooring and many other products.

When asbestos breaks down, as happens during the mining process or when it is removed from an insulation, dust is formed. If it is inhaled or swallowed, the fibers of the asbestos will lodge in the lungs or in the stomach, where they can cause irritation that, in turn, can cause a mesothelioma. It is not understood exactly how this happens. It may take 20 to 40 years or more for a mesothelioma to manifest itself after exposure to asbestos.

Most people who have been exposed to asbestos for years have never had mesothelioma. However, other people who were exposed very little time suffer from the disease. This indicates that other factors may be involved in determining whether someone contracts mesothelioma or not. For example, you could inherit a predisposition to cancer or some other disease could increase the risk.

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